At-Home Ketamine Therapy

At-Home Ketamine Therapy in Florida

A New Path Forward for Treatment-Resistant Depression, Anxiety & PTSD

If you've tried traditional medications or therapy and still haven't found the relief you're looking for, you're not alone — and there is hope. At MindZen, we offer personalized at-home ketamine therapy for individuals who have struggled to respond to conventional psychiatric treatment. This innovative approach is now available statewide across Florida, and is covered by most major insurance plans.

Now Accepting Insurance!

Self-pay rates as low as $125 per follow up*

Could Ketamine Therapy Be Right for You?

Ketamine therapy may be a good fit if you are 18 or older and have been experiencing symptoms of depression, anxiety, PTSD, or OCD that have not adequately responded to traditional treatment options. Many of our patients describe feeling "stuck" despite trying multiple medications or years of therapy — ketamine offers a different mechanism of action that may help where other treatments have fallen short.

How It Works

Ketamine works differently from traditional psychiatric medications. Rather than targeting serotonin or dopamine, ketamine acts on the brain's glutamate system and has been shown to increase BDNF (Brain-Derived Neurotrophic Factor) — a protein essential for the growth of new neural connections. This process, known as neuroplasticity, may help the brain "rewire" entrenched thought patterns and emotional responses, often with results that are felt more rapidly than with traditional antidepressants.

At MindZen, we use sublingual (under-the-tongue) ketamine, administered safely in the comfort of your own home under a personalized protocol developed by your provider.

Covered by Insurance — Self-Pay as Low as $125

One of the most common misconceptions about ketamine therapy is that it's out of reach financially. At MindZen, we have worked hard to change that. We are in-network with most major insurance providers and have kept our self-pay rates as low as $125 per follow-up session — a fraction of the cost of most ketamine clinics.

We accept: UnitedHealthcare, Cigna, Humana, Oscar, Blue Cross Blue Shield, Medicare, Tricare, Magellan, and Optum.

What to Expect

Initial Consultation

Your first appointment is a comprehensive evaluation where your provider will review your medical and psychiatric history, current medications, allergies, and symptoms to determine whether ketamine therapy is appropriate for you.

Your Treatment Plan

If you are found to be a good candidate, your provider will develop a personalized treatment plan covering safety protocols, medication administration, dosing, and follow-up care. A trusted adult sitter is required to be present during all sessions. Sessions typically last about one hour, and an at-home blood pressure cuff will be needed for monitoring.

Ongoing Support

Following your sessions, you will meet with your provider to discuss your experience, integrate insights from treatment, and assess whether any dosing adjustments are needed. Your provider is available Monday through Friday, 7am–7pm for any questions or concerns

Is Ketamine Therapy Safe?

Ketamine has been used in medical settings for decades and has a well-established safety profile at the sub-anesthetic doses used in psychiatric treatment. It is currently used off-label for mental health conditions, meaning it has not received FDA approval specifically for depression or anxiety — however, a substantial and growing body of clinical research supports its efficacy and tolerability for these uses.

Ketamine therapy may not be appropriate if any of the following apply:

Under 18 years old
Primary psychotic disorder
Active suicidal plan or attempt within the past year
Active substance use disorder concerns
Pregnancy or actively trying to conceive
Uncontrolled hypertension, heart failure, or serious cardiac conditions
High-dose benzodiazepine or narcotic use
Severe respiratory conditions (e.g., COPD)
Unstable thyroid disease
Elevated intracranial or intraocular pressure
Known ketamine allergy

Not sure if something applies to you? Call us at (813) 575-0477 and we'll talk through your specific situation.

What the Research Says

The evidence base for ketamine in psychiatric treatment is growing rapidly.

Below are several studies supporting its use:

1.) Retrospective study of off-label at-home sublingual ketamine use in 664 patients studying effects on depression/anxiety https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767816/

2.) "At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression" https://www.sciencedirect.com/science/article/pii/S0165032722007625

3.) Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8715255/

4.) Meta-analysis of twenty-eight studies demonstrating acute efficacy of sub anesthetic ketamine. https://www.sciencedirect.com/science/article/abs/pii/S0165032720327026

5.) Randomized controlled trial in 30 individuals with PTSD using IV ketamine vs midazolam control showing 67% response vs. 20% in control https://pubmed.ncbi.nlm.nih.gov/33397139/

6.) Open label study with 3 months of weekly subcutaneous ketamine at 1 mg/kg in 20 patients with txt resistant GAD and SAD. https://pubmed.ncbi.nlm.nih.gov/29561204/

7.) IV ketamine 0.5 mg/kg on depressive/anxiety features in 25 males with severe depression. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767816/

*It should be noted that many current studies do have smaller sample sizes and some of the studies listed do use alternative routes of ketamine administration which may have impact on outcome of studies when comparing to sublingual administration

Ready to Take the Next Step?

You deserve to feel better. If you've been struggling and are curious whether ketamine therapy might help, we'd love to have a conversation.

You can call or text us directly at 813-575-0477.

Email us at info@mindzenhealth.com

Click below to submit contact information and we will reach out to you to answer any questions or help schedule an initial appointment.

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At-Home Ketamine Therapy